According to the MTA there will be Roosevelt Island F Train service to and from Manhattan this weekend. But, the MTA adds:

F Service is rerouted in Manhattan and Brooklyn…

… No F service at 57 St, 47-50 Sts, 42 St-Bryant Pk, 23 St, 14 St, W 4 St, B’way-Lafayette St, 2 Av, Delancey St/Essex St, East Broadway, and York St.

F service operates between Jamaica-179 St and Lexington Av-63 St, and via the Q to/from Atlantic Av-Barclays Ctr (skipping DeKalb Av, days and evenings), and via the D to/from Stillwell Av.

Trains run express in Manhattan all weekend.

Also, no late night Roosevelt Island F Train service from Manhattan 11:45 PM to 5 AM

Monday thru Friday October 9- 13 and October 16- 20.