According to this June 30, 2026 press release from the World Monuments Fund:

World Monuments Fund (WMF) today announced Irreplaceable America, a new list recognizing 10 historic places across the United States whose preservation is essential to the richness and complexity of American history as the nation approaches the 250th anniversary of the Declaration of Independence. From landmarks of public health and colonial architecture to sites central to Black history, Indigenous heritage, and artistic experimentation, the initiative spotlights places facing urgent preservation needs.  

“The United States was built by people from every corner of the globe, shaped by Indigenous nations, early settlers, immigrant communities, and generations of cultural exchange,” said Bénédicte de Montlaur, President and CEO of World Monuments Fund. “That complexity gave rise to some of America’s most enduring contributions, from colonial heritage to jazz and hip-hop and the Wright brothers’ invention of powered flight. After decades of work at more than 700 sites in 113 countries, WMF has seen what communities gain when they can protect the places that matter and what is lost when they cannot. As the nation approaches its 250th anniversary, Irreplaceable America is a call to protect the places that reflect the richness of that history, and the role heritage plays in education, community memory, and civic life.”  

The list includes sites such as the Colonial Homes of Newport in Rhode Island; America’s First Smallpox Hospital on Roosevelt Island in New York; two of the most significant Mission Churches in New Mexico; the City of New Orleans in Louisiana; the African Meeting House in Massachusetts; and the Wright Brothers’ historic sites in Dayton, Ohio—reflecting both the breadth of American history and the range of preservation challenges these places face….

The World Monuments Fund Instagram page shows us the 10 Irreplaceable America historic sites being recognized including the Roosevelt Island Smallpox Hospital Ruins.

The World Monuments Fund reports on the Roosevelt Island Smallpox Hospital Ruins

New York’s Smallpox Hospital Ruin, Roosevelt Island, New York

The first U.S. facility built to treat epidemic disease, this nineteenth-century smallpox hospital, designed by architect James Renwick Jr., remains a rare landmark in the history of medicine. After decades of neglect, the structure faces structural instability and requires extensive stabilization to allow public access.

Constructed between 1854 and 1856 in the Gothic Revival style, the Smallpox Hospital was built on what is now Roosevelt Island to isolate contagious patients from dense urban populations. Its interior layout was optimized for ventilation and quarantine, while its granite walls, quarried on-site by prison labor, reflect both the ambitions and complexities of nineteenth-century public health infrastructure. But after decades of disuses, the structure fell into disrepair, leading to the collapse of the roof and interior floors.

Today, the ruin is a focal point of New York’s East River and seen daily from the city’s roadways and institutions such as the United Nations and the World Health Organization. In the aftermath of the COVID-19 pandemic, the site has gained renewed relevance as a place to reflect on epidemic disease, public health resilience, and the protection of vulnerable populations. Stabilization and adaptive reuse is an opportunity to preserve a civic landmark while providing a place of reflection on public health, memory, and urban life on Roosevelt Island’s waterfront.

“We’re thrilled that this remarkable building has been recognized as irreplaceable to the American story. Once a place of suffering, it now stands as a powerful reminder that determined public health can make a disease obsolete. That message feels especially urgent today.”   Stephen Martin, Founder, Friends of the Ruin 

Here’s more on the World Monuments Fund

and some of the incredible sites around the world protected by the World Monuments Fund.

Here’s a short film by Unforgotten Films showing us inside the Smallpox Hospital and potential plans to preserve the site by Friends of the Ruins.

Also, view from above the Smallpox Hospital.

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